Cardiovascular Fluid Dynamics Laboratory
Departments of Mechanical Engineering and Radiology

Publications

    2019

  1. Rutkowski DR, Barton G, François CJ, Bartlett HL, Anagnostopoulos PV and Roldán-Alzate A. Analysis of cavopulmonary and cardiac flow characteristics in fontan Patients: Comparison with healthy volunteers. Journal of magnetic resonance imaging : JMRI. 2019 June;49:1786-1799. DOI PMID
  2. Ruedinger KL, Medero R and Roldán-Alzate A. Fabrication of Low-Cost Patient-Specific Vascular Models for Particle Image Velocimetry. Cardiovascular engineering and technology. 2019 May DOI PMID
  3. Pewowaruk R and Roldán-Alzate A. 4D Flow MRI Estimation of Boundary Conditions for Patient Specific Cardiovascular Simulation. Annals of biomedical engineering. 2019 May DOI PMID
  4. Liu TT, Thomas S, Mclean DT, Roldan-Alzate A, Hernando D, Ricke EA and Ricke WA. Prostate enlargement and altered urinary function are part of the aging process. Aging. 2019 May;11:2653-2669. DOI PMID
  5. Rutkowski DR, Medero R, Garcia FJ and Roldán-Alzate A. MRI-based modeling of spleno-mesenteric confluence flow. Journal of biomechanics. 2019 March DOI PMID
  6. Motosugi U, Roldán-Alzate A, Bannas P, Said A, Kelly S, Zea R, Wieben O and Reeder SB. Four-dimensional Flow MRI as a Marker for Risk Stratification of Gastroesophageal Varices in Patients with Liver Cirrhosis. Radiology. 2019 January;290:101-107. DOI PMID

    7. 2018

  7. Ruesink T, Medero R, Rutkowski D and Roldán-Alzate A. In Vitro Validation of 4D Flow MRI for Local Pulse Wave Velocity Estimation. Cardiovascular engineering and technology. 2018 December;9:674-687. DOI PMID
  8. Medero R, Hoffman C and Roldán-Alzate A. Comparison of 4D Flow MRI and Particle Image Velocimetry Using an In Vitro Carotid Bifurcation Model. Annals of biomedical engineering. 2018 December;46:2112-2122. DOI PMID
  9. Ning J, Schubert T, Johnson K, Roldán-Alzate A, Chen H, Yuan C and Reeder S. Vascular input function correction of inflow enhancement for improved pharmacokinetic modeling of liver DCE-MRI. Magnetic Resonance in Medicine. 2018 November;79(6):3093-3102. DOI PMID
  10. Ruedinger KL, Zhou H, Trampe B, Heiser T, Srinivasan S, Iruretagoyena JI and Roldán-Alzate A. Modeling Fetal Cardiac Anomalies From Prenatal Echocardiography With 3-Dimensional Printing and 4-Dimensional Flow Magnetic Resonance Imaging. Circulation. Cardiovascular imaging. 2018 September;11:e007705. DOI PMID
  11. Ruedinger K, Rutkowski D, Schafer S, Roldán-Alzate A, Oberstar E and Strother C. Impact of image reconstruction parameters when using 3D DSA reconstructions to measure intracranial aneurysms. Journal of NeuroInterventional Surgery. 2018 April;10(3):285-289. DOI PMID

    12. 2017

  12. Frydrychowicz A, Roldan-Alzate A, Winslow E, Consigny D, Campo C, Motosugi U, Johnson K, Wieben O and Reeder S. Comparison of radial 4D Flow-MRI with perivascular ultrasound to quantify blood flow in the abdomen and introduction of a porcine model of pre-hepatic portal hypertension. European Radiology. 2017 June;27(12):5316-5324. DOI PMID
  13. Hussaini S, Rutkowski D, Roldán-Alzate A and François C. Left and right ventricular kinetic energy using time-resolved versus time-average ventricular volumes. Journal of Magnetic Resonance Imaging. 2017 March;45(3):821-828. DOI PMID
  14. Medero R, García-Rodríguez S, François C and Roldán-Alzate A. Patient-specific in vitro models for hemodynamic analysis of congenital heart disease – Additive manufacturing approach. Journal of Biomechanics. 2017 February;54:111-116. DOI PMID
  15. Rutkowski D, Reeder S, Fernandez L and Roldán-Alzate A. Surgical planning for living donor liver transplant using 4D flow MRI, computational fluid dynamics and in vitro experiments. Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization. 2017 January:1-11. DOI PMID
  16. Kellawan J, Harrell J, Roldan-Alzate A, Wieben O and Schrage W. Regional hypoxic cerebral vasodilation facilitated by diameter changes primarily in anterior versus posterior circulation. Journal of Cerebral Blood Flow and Metabolism. 2017 January;37(6):2025-2034. DOI PMID

    17. 2016

  17. Bannas P, Roldán-Alzate A, Johnson K, Woods M, Ozkan O, Motosugi U, Wieben O, Reeder S and Kramer H. Longitudinal monitoring of hepatic blood flow before and after TIPS by using 4D-flow MR imaging. Radiology. 2016 November;281(2):574-582. DOI PMID
  18. Roldán-Alzate A, Francois C, Wieben O and Reeder S. Emerging applications of abdominal 4D flow MRI. American Journal of Roentgenology. 2016 July;207(1):58-66. DOI PMID
  19. Mikhail Kellawan J, Harrell J, Schrauben E, Hoffman C, Roldan-Alzate A, Schrage W and Wieben O. Quantitative cerebrovascular 4D flow MRI at rest and during hypercapnia challenge. Magnetic Resonance Imaging. 2016 May;34(4):422-428. DOI PMID

    20. 2015

  20. Roldán-Alzate A, Frydrychowicz A, Said A, Johnson K, Francois C, Wieben O and Reeder S. Impaired regulation of portal venous flow in response to a meal challenge as quantified by 4D flow MRI. Journal of Magnetic Resonance Imaging. 2015 October;42(4):1009-1017. DOI PMID
  21. Roldán-Alzate A, García-Rodríguez S, Anagnostopoulos P, Srinivasan S, Wieben O and François C. Hemodynamic study of TCPC using in vivo and in vitro 4D Flow MRI and numerical simulation. Journal of Biomechanics. 2015 May;48(7):1325-1330. DOI PMID
  22. Jeong D, Anagnostopoulos P, Roldan-Alzate A, Srinivasan S, Schiebler M, Wieben O and François C. Ventricular kinetic energy may provide a novel noninvasive way to assess ventricular performance in patients with repaired tetralogy of Fallot. Journal of Thoracic and Cardiovascular Surgery. 2015 May;149(5):1339-1347. DOI PMID
  23. Barker A, Roldán-Alzate A, Entezari P, Shah S, Chesler N, Wieben O, Markl M and François C. Four-dimensional flow assessment of pulmonary artery flow and wall shear stress in adult pulmonary arterial hypertension: Results from two institutions. Magnetic Resonance in Medicine. 2015 May;73(5):1904-1913. DOI PMID
  24. Bellofiore A, Henningsen J, Lepak C, Tian L, Roldan-Alzate A, Kellihan H, Consigny D, Francois C and Chesler N. A Novel in Vivo Approach to Assess Radial and Axial Distensibility of Large and Intermediate Pulmonary Artery Branches. Journal of Biomechanical Engineering. 2015 April;137(4) DOI PMID

    25. 2014

  25. Forouzan O, Flink E, Warczytowa J, Thate N, Hanske A, Lee T, Roldan-Alzate A, François C, Wieben O and Chesler N. Low cost magnetic resonance imaging-compatible stepper exercise device for use in cardiac stress tests. Journal of Medical Devices, Transactions of the ASME. 2014 December;8(4) DOI PMID
  26. Tian L, Kellihan H, Henningsen J, Bellofiore A, Forouzan O, Roldán-Alzate A, Consigny D, Gunderson M, Dailey S, Francois C and Chesler N. Pulmonary artery relative area change is inversely related to ex vivo measured arterial elastic modulus in the canine model of acute pulmonary embolization. Journal of Biomechanics. 2014 September;47(12):2904-2910. DOI PMID
  27. Landgraf B, Johnson K, Roldán-Alzate A, Francois C, Wieben O and Reeder S. Effect of temporal resolution on 4D flow MRI in the portal circulation. Journal of Magnetic Resonance Imaging. 2014 April;39(4):819-826. DOI PMID
  28. Swift A, Wild J, Nagle S, Roldán-Alzate A, François C, Fain S, Johnson K, Capener D, Van Beek E, Kiely D, Wang K and Schiebler M. Quantitative magnetic resonance imaging of pulmonary hypertension: A practical approach to the current state of the art. Journal of Thoracic Imaging. 2014 March;29(2):68-79. DOI PMID
  29. Roldán-Alzate A, Frydrychowicz A, Johnson K, Kellihan H, Chesler N, Wieben O and François C. Non-invasive assessment of cardiac function and pulmonary vascular resistance in an canine model of acute thromboembolic pulmonary hypertension using 4D flow cardiovascular magnetic resonance. Journal of Cardiovascular Magnetic Resonance. 2014 March;16(1) DOI PMID
  30. Markovic L, Kellihan H, Roldán-Alzate A, Drees R, Bjorling D and Francois C. Advanced multimodality imaging of an anomalous vessel between the ascending aorta and main pulmonary artery in a dog. Journal of Veterinary Cardiology. 2014 March;16(1):59-65. DOI PMID
  31. Bannas P, Hernando D, Motosugi U, Roldan A and Reeder S. Emerging quantitative MRI biomarkers of diffuse liver disease. Clinical Liver Disease. 2014 January;4(6):129-132. DOI PMID

    32. 2013

  32. Schiebler M, Bhalla S, Runo J, Jarjour N, Roldan A, Chesler N and François C. Magnetic resonance and computed tomography imaging of the structural and functional changes of pulmonary arterial hypertension. Journal of Thoracic Imaging. 2013 May;28(3):178-195. DOI PMID
  33. Roldán-Alzate A, Frydrychowicz A, Niespodzany E, Landgraf B, Johnson K, Wieben O and Reeder S. In vivo validation of 4D flow MRI for assessing the hemodynamics of portal hypertension. Journal of Magnetic Resonance Imaging. 2013 May;37(5):1100-1108. DOI PMID
  34. Bellofiore A, Roldán-Alzate A, Besse M, Kellihan H, Consigny D, Francois C and Chesler N. Impact of acute pulmonary embolization on arterial stiffening and right ventricular function in dogs. Annals of Biomedical Engineering. 2013 January;41(1):195-204. DOI PMID

    35. 2012

  35. Artz N, Hines C, Brunner S, Agni R, Kühn J-P, Roldan-Alzate A, Chen G-H and Reeder S. Quantification of hepatic steatosis with dual-energy computed tomography: Comparison with tissue reference standards and quantitative magnetic resonance imaging in the ob/ob mouse. Investigative Radiology. 2012 October;47(10):603-610. DOI PMID
  36. Tabima D, Roldan-Alzate A, Wang Z, Hacker T, Molthen R and Chesler N. Persistent vascular collagen accumulation alters hemodynamic recovery from chronic hypoxia. Journal of Biomechanics. 2012 March;45(5):799-804. DOI PMID

    37. 2011

  37. Frydrychowicz A, Landgraf B, Niespodzany E, Verma R, Roldán-Alzate A, Johnson K, Wieben O and Reeder S. Four-dimensional velocity mapping of the hepatic and splanchnic vasculature with radial sampling at 3 Tesla: A feasibility study in portal hypertension. Journal of Magnetic Resonance Imaging. 2011 September;34(3):577-584. DOI PMID

    38. 2009

  38. Roldan A, Wieben O, Haughton V, Osswald T and Chesler N. Characterization of CSF hydrodynamics in the presence and absence of tonsillar ectopia by means of computational flow analysis. American Journal of Neuroradiology. 2009 May;30(5):941-946. DOI PMID

    39. 2008

  39. García S, Roldán A and Osswald T. Thin-wall injection molding – A dimensional analysis and scaling analysis approach [Dünnwandspritzgießen – eine Annäherung mittels Dimensionsanalyse und Skalierung]. Zeitschrift Kunststofftechnik/Journal of Plastics Technology. 2008(5)